{"product_id":"scyl2-polyclonal-antibody-e-ab-64490","title":"SCYL2 Polyclonal Antibody - E-AB-64490","description":"\u003cp\u003eSCYL2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-64490-60, E-AB-64490-120, E-AB-64490-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SCYL2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: SCYL2; CVAK104\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q6P3W7\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human SCYL2 (NP_060458.3).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:1000-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 103kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 103kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146332831923,"sku":"E-AB-64490-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146332864691,"sku":"E-AB-64490-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146332897459,"sku":"E-AB-64490-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_13059478-44f9-4910-bdab-11ce87a990c6.png?v=1710293782","url":"https:\/\/afsbio.com\/products\/scyl2-polyclonal-antibody-e-ab-64490","provider":"AFSBio Inc.","version":"1.0","type":"link"}