{"product_id":"sdhd-polyclonal-antibody-e-ab-91480","title":"SDHD Polyclonal Antibody - E-AB-91480","description":"\u003cp\u003eSDHD Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-91480-60, E-AB-91480-120, E-AB-91480-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SDHD\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: SDHD; CBT1; CII-4; CWS3; PGL; PGL1; QPs3; SDH4; cybS\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O14521\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human SDHD\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 9kDa\/12kDa\/15kDa\/17kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 17kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148801999027,"sku":"E-AB-91480-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148802031795,"sku":"E-AB-91480-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148802064563,"sku":"E-AB-91480-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_29640994-4e0d-490c-b1d2-f04cd7191087.png?v=1710330354","url":"https:\/\/afsbio.com\/products\/sdhd-polyclonal-antibody-e-ab-91480","provider":"AFSBio Inc.","version":"1.0","type":"link"}