{"product_id":"selh-rabbit-polyclonal-antibody-ra29712","title":"SELH Rabbit Polyclonal Antibody - RA29712","description":"SELH Rabbit Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA29712-50, RA29712-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: This gene encodes a nucleolar protein, which belongs to the SelWTH family. It functions as an oxidoreductase, and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways, promote mitochondrial biogenesis and mitochondrial function, and suppress cellular senescence through genome maintenance and redox regulation. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2016],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1：500-2000\n\nApplications: WB\n\nSpecies Cross-Reactivity: Human; Mouse\n\nGeneID (Human): 280636\n\nSWISS: Q8IZQ5\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119594266803,"sku":"RA29712-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119594299571,"sku":"RA29712-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9e999523-5e6c-4b0e-a800-00e8a29ae998.png?v=1773355158","url":"https:\/\/afsbio.com\/products\/selh-rabbit-polyclonal-antibody-ra29712","provider":"AFSBio Inc.","version":"1.0","type":"link"}