{"product_id":"sen2-polyclonal-antibody-bt-ap14114","title":"SEN2 Polyclonal Antibody - BT-AP14114","description":"\u003cp\u003eSEN2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14114-20, BT-AP14114-50, BT-AP14114-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TSEN2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: tRNA-splicing endonuclease subunit Sen2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8NCE0; Mouse: Q6P7W5; Rat: Q5M954\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: tRNA-splicing endonuclease subunit Sen2;EC 3.1.27.9;tRNA-intron endonuclease Sen2;HsSen2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 80746\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239342923955,"sku":"BT-AP14114-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239342956723,"sku":"BT-AP14114-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239342989491,"sku":"BT-AP14114-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_eaaada4b-e840-4edc-aa90-6146a0fe83c3.png?v=1769393292","url":"https:\/\/afsbio.com\/products\/sen2-polyclonal-antibody-bt-ap14114","provider":"AFSBio Inc.","version":"1.0","type":"link"}