{"product_id":"senp3-polyclonal-antibody-bt-ap08206","title":"SENP3 Polyclonal Antibody - BT-AP08206","description":"\u003cp\u003eSENP3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08206-20, BT-AP08206-50, BT-AP08206-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al. 2006 [PubMed 16738315]).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SENP3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SENP3 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 65010\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9H4L4; Mouse: Q9EP97\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SENP3; SSP3; SUSP3; Sentrin-specific protease 3; SUMO-1-specific protease 3; Sentrin\/SUMO-specific protease SENP3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 26168; Mouse: 80886\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239899160755,"sku":"BT-AP08206-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239899193523,"sku":"BT-AP08206-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239899226291,"sku":"BT-AP08206-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5102ec38-ea03-49dd-aa8b-64403156b31b.png?v=1769400648","url":"https:\/\/afsbio.com\/products\/senp3-polyclonal-antibody-bt-ap08206","provider":"AFSBio Inc.","version":"1.0","type":"link"}