{"product_id":"senp5-rabbit-pab-es3420","title":"SENP5 rabbit pAb - ES3420","description":"\u003cp\u003eSENP5 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3420-50, ES3420-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: SENP5; FKSG45; Sentrin-specific protease 5; Sentrin\/SUMO-specific protease SENP5\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Monkey\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human SENP5. AA range:651-700\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 86kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 205564\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q96HI0\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus, nucleolus.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202134106291,"sku":"ES3420-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202134139059,"sku":"ES3420-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_ca431900-90d4-408e-a3fb-9f319e5d4944.png?v=1767122712","url":"https:\/\/afsbio.com\/products\/senp5-rabbit-pab-es3420","provider":"AFSBio Inc.","version":"1.0","type":"link"}