{"product_id":"septin-3-polyclonal-antibody-bs62412","title":"Septin 3 Polyclonal Antibody-BS62412","description":"\u003cp\u003eSeptin 3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS62412-50, BS62412-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9UH03\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB:1:500~1:1000\u003c\/p\u003e \n\n\u003cp\u003eBackground: The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the Septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. Septin 10, a 517 residue polypeptide which localizes to the cytoplasm and nucleus, shares closest homology to Septin 6 and Septin 8. Septin 10 is expressed ubiquitously, though most abundantly in the placenta, lung, kidney, heart, skeletal muscles, liver and various tumor cell lines. Like other Septin family members, Septin 10 displays GTP-binding and GTPase activity. Additionally, Septin 10 is potentially involved in cytokinesis. Upon maturation induced by lipopolysaccharide (LPS), dendritic cells express upregulated amounts of Septin 10.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The protein was purified from E.coli and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Septin 3 polyclonal antibody detects endogenous levels of Septin 3 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Septin 3 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLaneA:The brain tissue lysate of Mouse\u003cbr\u003e\nLaneB:The brain tissue lysate of Rat\u003cbr\u003e\nLaneC:Hela whole cell lysate\u003cbr\u003e\nLaneD:The kidney tissue lysate of Mouse\u003cbr\u003e\nLaneE:The kidney tissue lysate of Rat\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 45 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Neuronal-specific septin-3; SEPTIN3; SEP3; SEPT3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human Septin 3.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910457036979,"sku":"BS62412-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910457069747,"sku":"BS62412-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a04a5bd2-1908-446e-85da-c55393140c58.jpg?v=1703092775","url":"https:\/\/afsbio.com\/products\/septin-3-polyclonal-antibody-bs62412","provider":"AFSBio Inc.","version":"1.0","type":"link"}