{"product_id":"septin-7-polyclonal-antibody-bt-ap08223","title":"Septin 7 Polyclonal Antibody - BT-AP08223","description":"\u003cp\u003eSeptin 7 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08223-20, BT-AP08223-50, BT-AP08223-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: SEPT7 encodes septin-7 that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SEPT7\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Septin 7 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 50680\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q16181; Mouse: O55131; Rat: Q9WVC0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SEPT7; CDC10; Septin-7; CDC10 protein homolog\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 989; Mouse: 235072; Rat: 64551\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239900831923,"sku":"BT-AP08223-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239900864691,"sku":"BT-AP08223-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239900897459,"sku":"BT-AP08223-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3551ed0a-1f58-4ac7-9439-b225760e8ab6.png?v=1769400667","url":"https:\/\/afsbio.com\/products\/septin-7-polyclonal-antibody-bt-ap08223","provider":"AFSBio Inc.","version":"1.0","type":"link"}