{"product_id":"serca1-atp2a1-rabbit-pab-a10104","title":"SERCA1\/ATP2A1 Rabbit pAb - A10104","description":"\u003cp\u003eSERCA1\/ATP2A1 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A10104-20, A10104-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 110kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 110kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 487\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O14983\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ATP2A; SERCA1; SERCA1\/ATP2A1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:200 - 1:1000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience, Calcium Signaling, Neurodegenerative Diseases, Cardiovascular, Heart, Cardiovascular diseases, Heart disease.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: ATP2A1\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189460394163,"sku":"A10104-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189460426931,"sku":"A10104-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_607705a7-e69e-4dd0-b246-1f3e94d7093b.png?v=1766427680","url":"https:\/\/afsbio.com\/products\/serca1-atp2a1-rabbit-pab-a10104","provider":"AFSBio Inc.","version":"1.0","type":"link"}