{"product_id":"serpin-a1-polyclonal-antibody-e-ab-40634","title":"Serpin A1 Polyclonal Antibody - E-AB-40634","description":"\u003cp\u003eSerpin A1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-40634-50, E-AB-40634-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Serpin A1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: alpha 1 Antitrypsin; Serpina1; Alpha-1-antiproteinase\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P17475\u003c\/p\u003e\n\n\u003cp\u003eBackground: Serpin A1 is the archetypal member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in the liver and secreted into the bloodstream with the major function to protect tissues against neutrophil elastase.A severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatitis, cirrhosis, and hepatocellular carcinoma.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 6.9mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Rat Serpin A1 protein expressed by E.coli\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen Affinity Purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB:1:100-1:200, IHC:1:2000-1:4000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 46kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43149055656115,"sku":"E-AB-40634-50","price":175.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43149055688883,"sku":"E-AB-40634-100","price":322.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_cda14a3a-846b-466e-a87e-4e8476d29293.png?v=1710339349","url":"https:\/\/afsbio.com\/products\/serpin-a1-polyclonal-antibody-e-ab-40634","provider":"AFSBio Inc.","version":"1.0","type":"link"}