{"product_id":"serpinb1-polyclonal-antibody-bs62099","title":"SERPINB1 Polyclonal Antibody-BS62099","description":"\u003cp\u003eSERPINB1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS62099-50, BS62099-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P30740\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. The monocyte\/neutrophil elastase inhibitor gene, SERPINB1, belongs to the Ov-serpin family (ovalbuminrelated serpins). Human SerpinB1, also designated monocyte\/neutrophil elastase inhibitor (M\/NEI) or leukocyte elastase inhibitor (LEI), is a cytoplasmic protein which acts as a fast-acting stoichiometric proteinase inhibitor that regulates the activity of neutrophil elastase (NE), cathepsin-G and proteinase-3. There are four homologous genes in mouse designated SerpinB1a, SerpinB1b, SerpinB1c and the pseudogene, Serpinb1-ps1. The three protein-coding genes share significant sequence identity, however SerpinB1a (also designated EIA) has been characterized as the functional ortholog of human SerpinB1.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: SERPINB1 polyclonal antibody detects endogenous levels of SERPINB1 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of SERPINB1 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane1:K562 whole cell lysate(40ug)\u003cbr\u003e\nLane2:The Spleen tissue lysate of Rat(40ug)\u003cbr\u003e\nLane3:The Spleen tissue lysate of Mouse(40ug)\u003cbr\u003e\nLane4:Myla2059 whole cell lysate(40ug)\u003cbr\u003e\nLane5:Jurkat whole cell lysate(40ug)\u003cbr\u003e\nLane6:A549 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 47 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Leukocyte elastase inhibitor; LEI; Monocyte\/neutrophil elastase inhibitor; EI; M\/NEI; Peptidase inhibitor 2; PI-2; Serpin B1; SERPINB1; ELANH2; MNEI; PI2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human SERPINB1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910467817651,"sku":"BS62099-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910467850419,"sku":"BS62099-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_cf0a9f6a-d26f-4bd5-a4b5-2117552886ca.jpg?v=1703092978","url":"https:\/\/afsbio.com\/products\/serpinb1-polyclonal-antibody-bs62099","provider":"AFSBio Inc.","version":"1.0","type":"link"}