{"product_id":"sesn3-polyclonal-antibody-e-ab-63213","title":"SESN3 Polyclonal Antibody - E-AB-63213","description":"\u003cp\u003eSESN3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-63213-60, E-AB-63213-120, E-AB-63213-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SESN3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: SESN3; SEST3; sestrin-3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Cardiovascular, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P58005\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine\/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human SESN3 (NP_653266.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:200-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 36kDa\/41kDa\/57kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 50kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146281648307,"sku":"E-AB-63213-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146281681075,"sku":"E-AB-63213-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146281713843,"sku":"E-AB-63213-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a0ab6bd8-3fef-4195-b3fc-448d0908ed43.png?v=1710292946","url":"https:\/\/afsbio.com\/products\/sesn3-polyclonal-antibody-e-ab-63213","provider":"AFSBio Inc.","version":"1.0","type":"link"}