{"product_id":"sesn3-rabbit-pab-a5164","title":"SESN3 Rabbit pAb - A5164","description":"\u003cp\u003eSESN3 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A5164-20, A5164-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine\/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 57kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 50kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 143686\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P58005\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: SEST3; SESN3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:200 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Tumor suppressors, Endocrine Metabolism, AMPK Signaling Pathway, Endocrine and metabolic diseases, Diabetes, Cardiovascular, Hypoxia.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: SESN3\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189934678195,"sku":"A5164-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189934710963,"sku":"A5164-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_825ced06-f33f-4549-8de2-acf45683e08d.png?v=1766438351","url":"https:\/\/afsbio.com\/products\/sesn3-rabbit-pab-a5164","provider":"AFSBio Inc.","version":"1.0","type":"link"}