{"product_id":"setb2-polyclonal-antibody-bt-ap14142","title":"SETB2 Polyclonal Antibody - BT-AP14142","description":"\u003cp\u003eSETB2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14142-20, BT-AP14142-50, BT-AP14142-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SETDB2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Histone-lysine N-methyltransferase SETDB2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q96T68; Mouse: Q8C267\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Histone-lysine N-methyltransferase SETDB2;EC 2.1.1.43;Chronic lymphocytic leukemia deletion region gene 8 protein;Lysine N-methyltransferase 1F;SET domain bifurcated 2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 83852\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239343546547,"sku":"BT-AP14142-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239343579315,"sku":"BT-AP14142-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239343612083,"sku":"BT-AP14142-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6a9aa5a3-69da-40f4-a004-a77a8b7e6ebd.png?v=1769393301","url":"https:\/\/afsbio.com\/products\/setb2-polyclonal-antibody-bt-ap14142","provider":"AFSBio Inc.","version":"1.0","type":"link"}