{"product_id":"setd2-monoclonal-antibody-bt-mca4669","title":"SETD2 Monoclonal Antibody - BT-MCA4669","description":"\u003cp\u003eSETD2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4669-50, BT-MCA4669-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SETD2\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4G11E6\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SETD2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human SETD2 (AA: 2054-2245) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 287.6kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9BYW2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: LLS, HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 29072\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238414442675,"sku":"BT-MCA4669-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238414475443,"sku":"BT-MCA4669-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_081ae55f-8c1e-4ecb-a387-32e8e4b47669.png?v=1769380342","url":"https:\/\/afsbio.com\/products\/setd2-monoclonal-antibody-bt-mca4669","provider":"AFSBio Inc.","version":"1.0","type":"link"}