{"product_id":"sf3b1-phospho-thr313-rabbit-polyclonal-antibody-bt-ap04709","title":"SF3B1 (Phospho-Thr313) Rabbit Polyclonal Antibody - BT-AP04709","description":"\u003cp\u003eSF3B1 (Phospho-Thr313) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04709-20, BT-AP04709-50, BT-AP04709-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b| together with splicing factor 3a and a 12S RNA unit| forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b\/3a complex binds pre-mRNA upstream of the intronandapos;s branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical| tandem HEAT repeats that form rod-like| helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SF3B1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SF3B1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O75533; Mouse: Q99NB9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SF3B1;Thr313; Splicing factor 3B subunit 1; Pre-mRNA-splicing factor SF3b 155 kDa subunit; SF3b155; Spliceosome-associated protein 155; SAP 155\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 23451\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239021600947,"sku":"BT-AP04709-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239021633715,"sku":"BT-AP04709-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239021666483,"sku":"BT-AP04709-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d2f58155-20da-42ed-9686-5f9159fdf6cf.png?v=1769388030","url":"https:\/\/afsbio.com\/products\/sf3b1-phospho-thr313-rabbit-polyclonal-antibody-bt-ap04709","provider":"AFSBio Inc.","version":"1.0","type":"link"}