{"product_id":"sf3b130-polyclonal-antibody-ra29758","title":"SF3b130 Polyclonal Antibody - RA29758","description":"SF3b130 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA29758-50, RA29758-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: splicing factor 3b subunit 3 (SF3B3) Homo sapiens This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP) . The splicing factor 3b\/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF (II) 31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF (II) -containing complex) . These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\n\nAlternative Names: SF3B3; KIAA0017; SAP130; Splicing factor 3B subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; SF3b130; STAF130; Spliceosome-associated protein 130; SAP 130\n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse\n\nGeneID (Human): 23450\n\nProtein MW (KDa): 140\n\nSWISS: Q15393\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122407104691,"sku":"RA29758-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122407137459,"sku":"RA29758-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5bf1d36b-70c0-4708-a085-49d032009deb.png?v=1773348532","url":"https:\/\/afsbio.com\/products\/sf3b130-polyclonal-antibody-ra29758","provider":"AFSBio Inc.","version":"1.0","type":"link"}