{"product_id":"sfrp1-polyclonal-antibody-bt-ap14149","title":"SFRP1 Polyclonal Antibody - BT-AP14149","description":"\u003cp\u003eSFRP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14149-20, BT-AP14149-50, BT-AP14149-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Developmental biology; Neuroscience; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SFRP1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Secreted frizzled-related protein 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8N474; Mouse: Q8C4U3; Rat: Q9R168\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Secreted frizzled-related protein 1;FRP-1;sFRP-1;Secreted apoptosis-related protein 2;SARP-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6422\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239344103603,"sku":"BT-AP14149-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239344136371,"sku":"BT-AP14149-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239344169139,"sku":"BT-AP14149-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8fbf0dd5-6378-48bf-b37a-5aafbb8106d6.png?v=1769393307","url":"https:\/\/afsbio.com\/products\/sfrp1-polyclonal-antibody-bt-ap14149","provider":"AFSBio Inc.","version":"1.0","type":"link"}