{"product_id":"sgk1-polyclonal-antibody-bt-ap08256","title":"SGK1 Polyclonal Antibody - BT-AP08256","description":"\u003cp\u003eSGK1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08256-20, BT-AP08256-50, BT-AP08256-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: SGK1 (serum\/glucocorticoid regulated kinase 1) encodes a serine\/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of SGK1 may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for SGK1.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SGK1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SGK1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 48942\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O00141; Mouse: Q9WVC6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SGK1; SGK; Serine\/threonine-protein kinase Sgk1; Serum\/glucocorticoid-regulated kinase 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6446\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239903387827,"sku":"BT-AP08256-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239903420595,"sku":"BT-AP08256-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239903453363,"sku":"BT-AP08256-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a3b9692f-2645-4c8e-8fe9-42c2c2b88d5c.png?v=1769400694","url":"https:\/\/afsbio.com\/products\/sgk1-polyclonal-antibody-bt-ap08256","provider":"AFSBio Inc.","version":"1.0","type":"link"}