{"product_id":"sgk3-phospho-thr320-rabbit-pab-es13133","title":"SGK3 (phospho-Thr320) rabbit pAb - ES13133","description":"\u003cp\u003eSGK3 (phospho-Thr320) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES13133-50, ES13133-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the Ser\/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Serine\/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum\/glucocorticoid-regulated kinase 3) (Serum\/glucocorticoid-regulated kinase-like)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthesized phosho peptide around human SGK3 (Thr320)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 54kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 100533105\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q96BR1\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasmic vesicle. Early endosome. Recycling endosome. Endosomal localization is a prerequisite for complete kinase activity. It is essential for its colocalization with the kinase responsible for phosphorylating Ser-486 thus allowing PDPK1 phosphorylation of Thr-320 resulting in complete activation of SGK3. Localized in vesicle-like structures and in the early endosome. Colocalizes with SLC9A3\/NHE3 in the recycling endosomes.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202402246835,"sku":"ES13133-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202402279603,"sku":"ES13133-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_6ff9fca3-7455-4bf7-80f4-699f7785e4e4.png?v=1767128392","url":"https:\/\/afsbio.com\/products\/sgk3-phospho-thr320-rabbit-pab-es13133","provider":"AFSBio Inc.","version":"1.0","type":"link"}