{"product_id":"sh2b2-monoclonal-antibody-bt-mca4598","title":"SH2B2 Monoclonal Antibody - BT-MCA4598","description":"\u003cp\u003eSH2B2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4598-50, BT-MCA4598-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc\/Grb2 pathway.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SH2B2\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5E11G7\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SH2B2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human SH2B2 (AA: 497-676) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 67.7kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O14492\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: APS\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10603\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238507536563,"sku":"BT-MCA4598-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238507569331,"sku":"BT-MCA4598-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d0b6b9c7-1782-4149-a843-c8a9435a7d7f.png?v=1769381971","url":"https:\/\/afsbio.com\/products\/sh2b2-monoclonal-antibody-bt-mca4598","provider":"AFSBio Inc.","version":"1.0","type":"link"}