{"product_id":"sh3bp2-polyclonal-antibody-e-ab-65749","title":"SH3BP2 Polyclonal Antibody - E-AB-65749","description":"\u003cp\u003eSH3BP2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-65749-60, E-AB-65749-120, E-AB-65749-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SH3BP2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: SH3BP2; 3BP-2; 3BP2; CRBM; CRPM; RES4-23\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P78314\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human SH3BP2 (NP_001116153.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 10kDa\/62kDa\/65kDa\/68kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 75kDa\/80kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148660539571,"sku":"E-AB-65749-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148660572339,"sku":"E-AB-65749-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148660605107,"sku":"E-AB-65749-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4fc938aa-b526-40ca-9c3a-04b7ca73d2b1.png?v=1710327507","url":"https:\/\/afsbio.com\/products\/sh3bp2-polyclonal-antibody-e-ab-65749","provider":"AFSBio Inc.","version":"1.0","type":"link"}