{"product_id":"sh3g3-polyclonal-antibody-bt-ap14189","title":"SH3G3 Polyclonal Antibody - BT-AP14189","description":"\u003cp\u003eSH3G3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14189-20, BT-AP14189-50, BT-AP14189-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes.,Implicated in endocytosis. May recruit other proteins to membranes with high curvature.,Belongs to the endophilin family.,Contains 1 BAR domain.,Contains 1 SH3 domain.,subcellular location:Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons.,subunit:Interacts with ARC (By similarity). Interacts with DNM1, SGIP1 and SYNJ1. Interacts with the huntingtin exon 1 protein (HDEX1P) containing a glutamine repeat in the pathological range and promotes formation of insoluble polyglutamine-containing aggregates in vivo.,tissue specificity:Brain and testis.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SH3GL3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Endophilin-A3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q99963; Mouse: Q62421; Rat: O35180\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Endophilin-A3;EEN-B2;Endophilin-3;SH3 domain protein 2C;SH3 domain-containing GRB2-like protein 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6457\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239346364595,"sku":"BT-AP14189-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239346397363,"sku":"BT-AP14189-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239346430131,"sku":"BT-AP14189-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f9fe1679-8797-43e7-af09-471a9d8906d9.png?v=1769393331","url":"https:\/\/afsbio.com\/products\/sh3g3-polyclonal-antibody-bt-ap14189","provider":"AFSBio Inc.","version":"1.0","type":"link"}