{"product_id":"sh3g3-rabbit-pab-es10255","title":"SH3G3 rabbit pAb - ES10255","description":"\u003cp\u003eSH3G3 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES10255-50, ES10255-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: domain:An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes., function:Implicated in endocytosis. May recruit other proteins to membranes with high curvature., similarity:Belongs to the endophilin family., similarity:Contains 1 BAR domain., similarity:Contains 1 SH3 domain., subcellular location:Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons., subunit:Interacts with ARC (By similarity). Interacts with DNM1, SGIP1 and SYNJ1. Interacts with the huntingtin exon 1 protein (HDEX1P) containing a glutamine repeat in the pathological range and promotes formation of insoluble polyglutamine-containing aggregates in vivo., tissue specificity:Brain and testis.,\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 38kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 6457\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q99963\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Early endosome membrane; Peripheral membrane protein. Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201721131187,"sku":"ES10255-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201721163955,"sku":"ES10255-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_c91cfe02-d768-4330-bcb4-d6b140c3faad.png?v=1767110237","url":"https:\/\/afsbio.com\/products\/sh3g3-rabbit-pab-es10255","provider":"AFSBio Inc.","version":"1.0","type":"link"}