{"product_id":"sh3tc2-polyclonal-antibody-bt-ap08283","title":"SH3TC2 Polyclonal Antibody - BT-AP08283","description":"\u003cp\u003eSH3TC2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08283-20, BT-AP08283-50, BT-AP08283-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: SH3TC2 (SH3 domain and tetratricopeptide repeats 2) encodes a protein with two N-terminal Src homology 3 (SH3) domains and 10 tetratricopeptide repeat (TPR) motifs, and is a member of a small gene family. The gene product has been proposed to be an adapter or docking molecule. Mutations in this gene result in autosomal recessive Charcot-Marie-Tooth disease type 4C, a childhood-onset neurodegenerative disease characterized by demyelination of motor and sensory neurons.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SH3TC2\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SH3TC2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 144777\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8TF17; Mouse: Q80VA5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SH3TC2; KIAA1985; PP12494; SH3 domain and tetratricopeptide repeat-containing protein 2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 79628\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239905190067,"sku":"BT-AP08283-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239905222835,"sku":"BT-AP08283-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239905255603,"sku":"BT-AP08283-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d3320d7f-17e5-4527-ba63-d4c51f09eb41.png?v=1769400715","url":"https:\/\/afsbio.com\/products\/sh3tc2-polyclonal-antibody-bt-ap08283","provider":"AFSBio Inc.","version":"1.0","type":"link"}