{"product_id":"shpk-polyclonal-antibody-e-ab-52517","title":"SHPK Polyclonal Antibody - E-AB-52517","description":"\u003cp\u003eSHPK Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-52517-60, E-AB-52517-120, E-AB-52517-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SHPK\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Carbohydrate kinase like; Carbohydrate kinase like protein; Carbohydrate kinase-like protein; CARKL; Sedoheptulokinase; SHK; Shpk; SHPK\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9UHJ6\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human SHPK\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 51 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143959576755,"sku":"E-AB-52517-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143959609523,"sku":"E-AB-52517-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143959642291,"sku":"E-AB-52517-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_067e3cc4-24f8-483d-941d-cf03c14d003d.png?v=1710244379","url":"https:\/\/afsbio.com\/products\/shpk-polyclonal-antibody-e-ab-52517","provider":"AFSBio Inc.","version":"1.0","type":"link"}