{"product_id":"siah-2-polyclonal-antibody-bt-ap08306","title":"Siah-2 Polyclonal Antibody - BT-AP08306","description":"\u003cp\u003eSiah-2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08306-20, BT-AP08306-50, BT-AP08306-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: SIAH2 encodes E3 ubiquitin-protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SIAH2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Siah-2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 34615\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O43255; Mouse: Q06986; Rat: Q8R4T2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SIAH2; E3 ubiquitin-protein ligase SIAH2; Seven in absentia homolog 2; Siah-2; hSiah2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6478; Mouse: 20439; Rat: 140593\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239906926771,"sku":"BT-AP08306-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239906959539,"sku":"BT-AP08306-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239906992307,"sku":"BT-AP08306-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_51186c93-808a-4701-baf7-3db148d5cd3a.png?v=1769400743","url":"https:\/\/afsbio.com\/products\/siah-2-polyclonal-antibody-bt-ap08306","provider":"AFSBio Inc.","version":"1.0","type":"link"}