{"product_id":"sial-polyclonal-antibody-bt-ap14218","title":"SIAL Polyclonal Antibody - BT-AP14218","description":"\u003cp\u003eSIAL Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14218-20, BT-AP14218-50, BT-AP14218-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: IBSP\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Bone sialoprotein 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P21815; Mouse: Q61711; Rat: P13839\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Bone sialoprotein 2;Bone sialoprotein II;BSP II;Cell-binding sialoprotein;Integrin-binding sialoprotein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3381\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239347151027,"sku":"BT-AP14218-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239347183795,"sku":"BT-AP14218-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239347216563,"sku":"BT-AP14218-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_67b923f1-b7e3-4863-aac3-9c1dc5f1daa6.png?v=1769393344","url":"https:\/\/afsbio.com\/products\/sial-polyclonal-antibody-bt-ap14218","provider":"AFSBio Inc.","version":"1.0","type":"link"}