{"product_id":"siglec3-cd33-polyclonal-antibody-e-ab-60582","title":"SIGLEC3\/CD33 Polyclonal Antibody - E-AB-60582","description":"\u003cp\u003eSIGLEC3\/CD33 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60582-60, E-AB-60582-120, E-AB-60582-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SIGLEC3\/CD33\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CD33; SIGLEC-3; SIGLEC3; p67\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P20138\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD33 is a 67 kD type I transmembrane glycoprotein also known as Siglec-3, gp67, and p67. It is a sialoadhesion immunoglobulin superfamily member expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes and hematopoietic stem cells. CD33 functions as a sialic acid-dependent cell adhesion molecule with carbohydrate\/lectin binding activity.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human SIGLEC3\/CD33 (NP_001763.3).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IHC \t1:50-1:200   IF \t1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 25kDa\/33kDa\/39kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 70kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146087661747,"sku":"E-AB-60582-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146087694515,"sku":"E-AB-60582-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146087727283,"sku":"E-AB-60582-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_792dd041-4d31-4796-8eb6-632cbb44f8c2.png?v=1710290823","url":"https:\/\/afsbio.com\/products\/siglec3-cd33-polyclonal-antibody-e-ab-60582","provider":"AFSBio Inc.","version":"1.0","type":"link"}