{"product_id":"siglec5-polyclonal-antibody-e-ab-11046","title":"SIGLEC5 Polyclonal Antibody - E-AB-11046","description":"\u003cp\u003eSIGLEC5 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-11046-60, E-AB-11046-120, E-AB-11046-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SIGLEC5\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CD170; CD170 antigen; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OB-BP2; OBBP2; Obesity-binding protein 2; Sialic acid binding Ig-like lectin 5; Sialic acid binding immunoglobulin-like lectin 5; Sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; SIGL5; Siglec-5; Siglec-F variant; Siglec5; Siglecf\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O15389\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human SIGLEC5\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:25-1:100\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124068450483,"sku":"E-AB-11046-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124068483251,"sku":"E-AB-11046-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124068516019,"sku":"E-AB-11046-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5ef458a8-dcea-460d-bb8f-d1eb43a58339.png?v=1709723340","url":"https:\/\/afsbio.com\/products\/siglec5-polyclonal-antibody-e-ab-11046","provider":"AFSBio Inc.","version":"1.0","type":"link"}