Concentrated solution of Bovine Serum Albumin (BSA) conjugated to Sirolimus. A carbon spacer arm of 19.0 Å links BSA to the Sirolimus moiety. Each BSA molecule contains several Sirolimus units. Dilutions of the provided conjugate can be made in 1X Phosphate Buffer Saline, pH 7.4.
|Product Data Sheet||Download PDF|
|Package Size:||0.5 mg|
|Molecular Weight:||71 kDa (average)|
|Storage:||-20°C. Avoid repeated freeze/thaw cycles.|
|Other names:||BSA-Sirolimus, Sirolimus-BSA, BSA conjugated to Sirolimus, Sirolimus Bovine Serum Albumin Conjugate, Sirolimus [BSA], BSA- Rapamycin, Rapamycin -BSA, BSA conjugated to Rapamycin, Rapamycin Bovine Serum Albumin Conjugate, Rapamycin [BSA]|
|Keywords:||BSA conjugate, Sirolimus, (-)-Rapamycin; Rapamycin; Sirolimús; Sirolimusum|
|Buffer:||1X Phosphate Buffer Saline, pH 7.4.|
Also known as Rapamycin, Sirolimus is a cyclic macrolide naturally produced by a strain of Streptomyces hygroscopicus. The name Rapamycin derives from the name of the island where the fungus was first isolated: Rapa Nui, also known as Easter Island. Sirolimus originally exhibited antifungal activities and later found to have immunosuppressive and antitumor activities. Sirolimus inhibits the production of cytokines by blocking the transcriptional activation of cytokine genes.
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