{"product_id":"sirt2-monoclonal-antibody-bt-mca3539","title":"SIRT2 Monoclonal Antibody - BT-MCA3539","description":"\u003cp\u003eSIRT2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3539-50, BT-MCA3539-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SIRT2\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5H11H9\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SIRT2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human SIRT2 (AA: 275-389) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 43.2kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q8IXJ6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SIR2, SIR2L, SIR2L2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 22933\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238378889395,"sku":"BT-MCA3539-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238378922163,"sku":"BT-MCA3539-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3116eb31-765d-4351-b073-ad9ad9029e70.png?v=1769379516","url":"https:\/\/afsbio.com\/products\/sirt2-monoclonal-antibody-bt-mca3539","provider":"AFSBio Inc.","version":"1.0","type":"link"}