{"product_id":"sirt6-rabbit-pab-a7416","title":"SIRT6 Rabbit pAb - A7416","description":"\u003cp\u003eSIRT6 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A7416-20, A7416-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables several functions, including NAD (P) +-protein-arginine ADP-ribosyltransferase activity; NAD-dependent histone deacetylase activity (H3-K9 specific) ; and transcription corepressor activity. Involved in several processes, including cellular protein modification process; negative regulation of nucleobase-containing compound metabolic process; and positive regulation of cell population proliferation. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; gonad; musculature; and retina. Used to study progeria. Orthologous to human SIRT6 (sirtuin 6) .\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 36 kDa\/39 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 36-42 kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 50721\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q8N6T7\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Sir2l6; mSIRT6; 2810449N18Rik; SIRT6\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics \u0026amp; Nuclear Signaling, Chromatin Modifying Enzymes, Deacetylation.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Sirt6\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45190037012659,"sku":"A7416-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45190037045427,"sku":"A7416-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_ef5e0859-a647-4810-aceb-5e530bc4e6c9.png?v=1766440416","url":"https:\/\/afsbio.com\/products\/sirt6-rabbit-pab-a7416","provider":"AFSBio Inc.","version":"1.0","type":"link"}