{"product_id":"skp2-phospho-ser64-rabbit-polyclonal-antibody-bt-ap04761","title":"Skp2 (Phospho-Ser64) Rabbit Polyclonal Antibody - BT-AP04761","description":"\u003cp\u003eSkp2 (Phospho-Ser64) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04761-20, BT-AP04761-50, BT-AP04761-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box| this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B| also referred to as p27 or KIP1) predominantly in S phase and int\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Cardiovascular; Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SKP2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Skp2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13309; Mouse: Q9Z0Z3\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Skp2;Ser64; S-phase kinase-associated protein 2; Cyclin-A\/CDK2-associated protein p45; F-box protein Skp2; F-box\/LRR-repeat protein 1; p45skp2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6502; Mouse: 27401\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239022715059,"sku":"BT-AP04761-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239022747827,"sku":"BT-AP04761-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239022780595,"sku":"BT-AP04761-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9fbe7b20-59d7-41b3-94c6-af96802cf95f.png?v=1769388043","url":"https:\/\/afsbio.com\/products\/skp2-phospho-ser64-rabbit-polyclonal-antibody-bt-ap04761","provider":"AFSBio Inc.","version":"1.0","type":"link"}