{"product_id":"skp2-phospho-ser64-rabbit-polyclonal-antibody-ra29850","title":"Skp2 (phospho-Ser64) Rabbit Polyclonal Antibody - RA29850","description":"\u003cp\u003eSkp2 (phospho-Ser64) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA29850-50, RA29850-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: S-phase kinase associated protein 2 (SKP2) Homo sapiens This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and int\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: S-phase kinase-associated protein 2 (Cyclin-A\/CDK2-associated protein p45) (F-box protein Skp2) (F-box\/LRR-repeat protein 1) (p45skp2)\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 6502\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 47\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q13309\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122411430067,"sku":"RA29850-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122411462835,"sku":"RA29850-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_624b5a38-c18e-4950-b395-0c90b77bb6dc.png?v=1773348582","url":"https:\/\/afsbio.com\/products\/skp2-phospho-ser64-rabbit-polyclonal-antibody-ra29850","provider":"AFSBio Inc.","version":"1.0","type":"link"}