{"product_id":"slc12a3-polyclonal-antibody-e-ab-92031","title":"SLC12A3 Polyclonal Antibody - E-AB-92031","description":"SLC12A3 Polyclonal Antibody\n\nSizes: 60μL, 120μL, 200μL\n\nCatalogue Numbers: E-AB-92031-60, E-AB-92031-120, E-AB-92031-200\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: SLC12A3\n\nTarget Synonym: NCC; NCCT; TSC; SLC12A3\n\nConjugation: Unconjugated\n\nHost: Rabbit\n\nSpecies Reactivity: Human, Mouse, Monkey\n\nApplication: WB\n\nIsotype: IgG\n\nClonality: Polyclonal\n\nUNIProt ID: P55017\n\nBackground: This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]\n\nConcentration: 1mg\/mL\n\nImmunogen: Recombinant fusion protein of human SLC12A3\n\nBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\n\nPurification Method: Affinity purification\n\nDilution: WB 1:500-1:2000\n\nObserved MW: 100-170KDa\n\nStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\n\nShipping: Ice bag\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43144112799923,"sku":"E-AB-92031-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43144112832691,"sku":"E-AB-92031-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43144112865459,"sku":"E-AB-92031-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_45c6b3e9-60a6-4a2a-ba28-a282367f8d10.png?v=1710246517","url":"https:\/\/afsbio.com\/products\/slc12a3-polyclonal-antibody-e-ab-92031","provider":"AFSBio Inc.","version":"1.0","type":"link"}