{"product_id":"slc16a13-l423-polyclonal-antibody-bs3143","title":"SLC16A13 (L423) Polyclonal Antibody-BS3143","description":"\u003cp\u003eSLC16A13 (L423) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3143-50, BS3143-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Monocarboxylate transporter 13; MCT 13; Solute carrier family 16 member 13; SLC16A13; MCT13\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q7RTY0\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: SLC16A13 (L423) polyclonal antibody detects endogenous levels of SLC16A13 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 40 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of SLC16A13 (L423) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: C6 whole cell lysate(40ug)\u003cbr\u003e\nLane 2: 3T3-L1 whole cell lysate(40ug)\u003cbr\u003e\nLane 3: MCF-7 whole cell lysate(40ug)\u003cbr\u003e\nLane 4: HepG2 whole cell lysate(40ug)\u003cbr\u003e\nLane 5: H1792 whole cell lysate(20ug)\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 389-442 of Human SLC16A13.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42911802196147,"sku":"BS3143-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42911802228915,"sku":"BS3143-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_d245c8e8-db18-47f7-9cbe-122611b4f106.jpg?v=1703179502","url":"https:\/\/afsbio.com\/products\/slc16a13-l423-polyclonal-antibody-bs3143","provider":"AFSBio Inc.","version":"1.0","type":"link"}