{"product_id":"smac-monoclonal-antibody-mb11607","title":"SMAC Monoclonal Antibody-MB11607","description":"\u003cp\u003eSMAC Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB11607-50, MB11607-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9NR28\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-F, IHC-P, ICC\/IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Smac\/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac\/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac\/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 27 kDa; Observed MW: 21 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Smac\/Diablo in mouse heart, rat skin lysates using SMAC antibody., Western blot analysis of Smac\/Diablo in K562, Hela lysates using Smac\/Diablo antibody., Immunocytochemistry analysis of Smac\/Diablo in Hela using Smac\/Diablo antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human tonsil using Smac\/Diablo antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: SMAC; DFNA64; DIABLO; SMAC3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human Smac\/Diablo\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43055909470387,"sku":"MB11607-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43055909503155,"sku":"MB11607-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_bc3e40ff-632d-4002-9516-ba644be714de.jpg?v=1708086552","url":"https:\/\/afsbio.com\/products\/smac-monoclonal-antibody-mb11607","provider":"AFSBio Inc.","version":"1.0","type":"link"}