{"product_id":"smad3-monoclonal-antibody-8b5-bt-mca1133","title":"Smad3 Monoclonal Antibody (8B5) - BT-MCA1133","description":"\u003cp\u003eSmad3 Monoclonal Antibody (8B5)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA1133-20, BT-MCA1133-50, BT-MCA1133-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Epigenetics and nuclear signaling; Cancer; Stem cells; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SMAD3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Rat,Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Mothers against decapentaplegic homolog 3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P84022; Mouse: Q8BUN5; Rat: P84025\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4088\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240047730867,"sku":"BT-MCA1133-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240047763635,"sku":"BT-MCA1133-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240047796403,"sku":"BT-MCA1133-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c360ec1f-dd7f-4b70-9000-5456e12b805b.png?v=1769402654","url":"https:\/\/afsbio.com\/products\/smad3-monoclonal-antibody-8b5-bt-mca1133","provider":"AFSBio Inc.","version":"1.0","type":"link"}