{"product_id":"smad3-phospho-ser423-425-rabbit-polyclonal-antibody-bt-ap12684","title":"Smad3 (Phospho-Ser423\/425) Rabbit Polyclonal Antibody - BT-AP12684","description":"\u003cp\u003eSmad3 (Phospho-Ser423\/425) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12684-20, BT-AP12684-50, BT-AP12684-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the SMAD| a family of proteins similar to the gene products of the Drosophila gene andapos;mothers against decapentaplegicandapos; (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Signal transduction; Metabolism; Cancer; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SMAD3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Smad3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P84022; Mouse: Q8BUN5; Rat: P84025\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Smad3;Ser423\/425; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4088; Mouse: 17127; Rat: 25631\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239023206579,"sku":"BT-AP12684-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239023239347,"sku":"BT-AP12684-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239023272115,"sku":"BT-AP12684-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6596af77-e63a-4e98-8075-03c5f0784883.png?v=1769388049","url":"https:\/\/afsbio.com\/products\/smad3-phospho-ser423-425-rabbit-polyclonal-antibody-bt-ap12684","provider":"AFSBio Inc.","version":"1.0","type":"link"}