{"product_id":"smc1a-polyclonal-antibody-bz16703","title":"SMC1A Polyclonal Antibody - BZ16703","description":"\u003cp\u003eSMC1A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16703-50, BZ16703-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair . ATM\/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Chromosome segregation protein SmcB, DXS423E, KIAA0178, MGC138332, Sb1.8, Segregation of mitotic chromosomes 1, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1 (structural maintenance of chromosomes 1 yeast) like 1, SMC1, SMC1 structural maintenance of chromosomes 1 like 1, SMC1A, SMC1A_HUMAN, SMC1alpha, SMC1L1, SMCB, Structural maintenance of chromosomes 1A, Structural maintenance of chromosomes protein 1A.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human SMC1\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1\/500-1\/1000 IHC: 1\/50-1\/100 IF: 1\/50-1\/200\u003c\/p\u003e \n\n\u003cp\u003ePurification: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Calcμlated MW: 143 kDa, Observed MW: 143 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q14683\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45945833390259,"sku":"BZ16703-50","price":349.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45945833423027,"sku":"BZ16703-100","price":582.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/smc1a-polyclonal-antibody-bz16703","provider":"AFSBio Inc.","version":"1.0","type":"link"}