{"product_id":"smc6-polyclonal-antibody-bs65989","title":"SMC6 Polyclonal Antibody-BS65989","description":"\u003cp\u003eSMC6 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65989-50, BS65989-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q96SB8\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSMC6 Polyclonal Antibody-BS65989\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-P\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC-P=1:100-500\u003c\/p\u003e\n\n\u003cp\u003eBackground: SMC5\/6 complex is recruited to nuclease induced double strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs. The human SMC5\/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells.\u003c\/p\u003e\n\n\n\u003cp\u003ePurification and Purity: affinity purified by Protein A\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: SMC6 Polyclonal Antibody detects endogenous levels of SMC6  protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 126 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Paraformaldehyde-fixed, paraffin embedded (rat stomach)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SMC6) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C,, Paraformaldehyde-fixed, paraffin embedded (rat lung)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SMC6) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: SMC6L1; SMC 6; SMC6; SMC6 protein; SMC6 structural maintenance of chromosomes 6 like 1; Structural maintenance of chromosomes 6; Structural maintenance of chromosomes 6 like 1; Structural maintenance of chromosomes protein 6.\u003c\/p\u003e \n\n\n\u003cp\u003eImmunogen: KLH conjugated synthetic peptide derived from human SMC6:155-260\/1091\u003c\/p\u003e \n\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962783502515,"sku":"BS65989-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962783535283,"sku":"BS65989-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_38883747-5dc9-4b05-98dc-fe3210e8c05a.jpg?v=1705318927","url":"https:\/\/afsbio.com\/products\/smc6-polyclonal-antibody-bs65989","provider":"AFSBio Inc.","version":"1.0","type":"link"}