{"product_id":"smce1-polyclonal-antibody-bt-ap14320","title":"SMCE1 Polyclonal Antibody - BT-AP14320","description":"\u003cp\u003eSMCE1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14320-20, BT-AP14320-50, BT-AP14320-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI\/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI\/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI\/SNF complex. Unlike most of the SWI\/SNF complex proteins, this protein has no yeast counterpart.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SMARCE1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q969G3; Mouse: O54941; Rat: Q56A18\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1;BRG1-associated factor 57;BAF57\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6605\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239351771315,"sku":"BT-AP14320-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239351804083,"sku":"BT-AP14320-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239351836851,"sku":"BT-AP14320-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d0aec9d7-4eb5-4a24-9b1d-2adcda4c8fc0.png?v=1769393413","url":"https:\/\/afsbio.com\/products\/smce1-polyclonal-antibody-bt-ap14320","provider":"AFSBio Inc.","version":"1.0","type":"link"}