{"product_id":"snai2-monoclonal-antibody-bt-mca4755","title":"SNAI2 Monoclonal Antibody - BT-MCA4755","description":"\u003cp\u003eSNAI2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4755-50, BT-MCA4755-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in gamma-irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience, Cancer, Stem cells, Epigenetics and nuclear signaling, Developmental biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SNAI2\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2H5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SNAI2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human SNAI2 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 30kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O43623\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SLUG, WS2D, SLUGH1, MGC10182, SNAI2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 6591\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238427058355,"sku":"BT-MCA4755-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238427091123,"sku":"BT-MCA4755-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f2fd3d69-e67d-4a52-b578-fd2868986da3.png?v=1769380624","url":"https:\/\/afsbio.com\/products\/snai2-monoclonal-antibody-bt-mca4755","provider":"AFSBio Inc.","version":"1.0","type":"link"}