{"product_id":"snca-polyclonal-antibody-e-ab-64580","title":"SNCA Polyclonal Antibody - E-AB-64580","description":"\u003cp\u003eSNCA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-64580-60, E-AB-64580-120, E-AB-64580-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SNCA\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PD1; NACP; PARK1; PARK4; SNCA\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P37840\u003c\/p\u003e\n\n\u003cp\u003eBackground: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human SNCA\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 11kDa\/13kDa\/14kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 18KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146340466867,"sku":"E-AB-64580-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146340499635,"sku":"E-AB-64580-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146340532403,"sku":"E-AB-64580-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c501f5b9-39e9-4120-b4da-2bef317834c0.png?v=1710293854","url":"https:\/\/afsbio.com\/products\/snca-polyclonal-antibody-e-ab-64580","provider":"AFSBio Inc.","version":"1.0","type":"link"}