{"product_id":"snx6-polyclonal-antibody-e-ab-17861","title":"SNX6 Polyclonal Antibody - E-AB-17861","description":"\u003cp\u003eSNX6 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-17861-60, E-AB-17861-120, E-AB-17861-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SNX6\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Sorting Nexin 6; Tumor Necrosis Factor Receptor-Associated Factor 4(TRAF4)-Associated Factor 2; MSTP010; TFAF2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction,Stem Cells,Developmental Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9UNH7\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.6 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human SNX6\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:40-1:200, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130660978867,"sku":"E-AB-17861-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130661011635,"sku":"E-AB-17861-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130661044403,"sku":"E-AB-17861-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1b5ff6bd-7f5f-4012-8474-25d79f981aa6.png?v=1709810963","url":"https:\/\/afsbio.com\/products\/snx6-polyclonal-antibody-e-ab-17861","provider":"AFSBio Inc.","version":"1.0","type":"link"}