{"product_id":"socs3-monoclonal-antibody-bt-mca4817","title":"SOCS3 Monoclonal Antibody - BT-MCA4817","description":"\u003cp\u003eSOCS3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4817-50, BT-MCA4817-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction, Epigenetics and nuclear signaling, Cancer, Stem cells, Metabolism, Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SOCS3\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5E12E7F1\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SOCS3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human SOCS3 (AA: 1-225) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 24.8KDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O14543\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 9021\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238521921715,"sku":"BT-MCA4817-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238521954483,"sku":"BT-MCA4817-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5d9df2f7-a6df-4ef7-8798-c62fbfb16882.png?v=1769382140","url":"https:\/\/afsbio.com\/products\/socs3-monoclonal-antibody-bt-mca4817","provider":"AFSBio Inc.","version":"1.0","type":"link"}