{"product_id":"sod1-rabbit-pab-es20629","title":"SOD1 rabbit pAb - ES20629","description":"\u003cp\u003eSOD1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20629-50, ES20629-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000.IHC-p:1:50-300. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from the Internal region of human SOD-1.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 18kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 6647\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P00441\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Mitochondrion. Nucleus. Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201965940915,"sku":"ES20629-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201965973683,"sku":"ES20629-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_60338c73-8ee1-44cc-a372-b8af1ec498a9.png?v=1767119022","url":"https:\/\/afsbio.com\/products\/sod1-rabbit-pab-es20629","provider":"AFSBio Inc.","version":"1.0","type":"link"}