{"product_id":"sod2-polyclonal-antibody-bt-ap14364","title":"SOD2 Polyclonal Antibody - BT-AP14364","description":"\u003cp\u003eSOD2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14364-20, BT-AP14364-50, BT-AP14364-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the iron\/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Neuroscience; Cell biology; Metabolism; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SOD2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Superoxide dismutase [Mn], mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P04179; Mouse: P09671; Rat: P07895\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Superoxide dismutase [Mn], mitochondrial; SOD2; Superoxide dismutase [Mn; , mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6648\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239356981427,"sku":"BT-AP14364-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239357014195,"sku":"BT-AP14364-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239357046963,"sku":"BT-AP14364-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_12cfccfa-84d3-4452-8363-5a9e54912b75.png?v=1769393442","url":"https:\/\/afsbio.com\/products\/sod2-polyclonal-antibody-bt-ap14364","provider":"AFSBio Inc.","version":"1.0","type":"link"}