{"product_id":"sos-2-rabbit-polyclonal-antibody-es7253","title":"Sos 2 Rabbit Polyclonal Antibody - ES7253","description":"\u003cp\u003eSos 2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES7253-50, ES7253-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse,\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA, IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: SOS2, Son of sevenless homolog 2, SOS-2\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human SOS2. AA range:631-680\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: Sos 2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Sos 2 Polyclonal Antibody detects endogenous levels of Sos 2 protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, IHC-p 1:50-300, ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Brain, Placenta,\u003c\/p\u003e \n\n\u003cp\u003eObserved Band (KD): 150kD\u003c\/p\u003e\n\n\u003cp\u003eFields: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, mTOR signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Thermogenesis, Neurotrophin signaling pathway, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Relaxin signaling pathway, Growth hormone synthesis, secretion and action, Alcoholism, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Che\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Promotes the exchange of Ras-bound GDP by GTP\u003cbr\u003e\nOnline Information: Son of sevenless entry,Similarity: Contains 1 DH (DBL-homology) domain\u003cbr\u003e\nSimilarity: Contains 1 N-terminal Ras-GEF domain\u003cbr\u003e\nSimilarity: Contains 1 PH domain\u003cbr\u003e\nSimilarity: Contains 1 Ras-GEF domain\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: intracellular, cytosol,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: SOS2\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Son of sevenless homolog 2\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q02384\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46313706324147,"sku":"ES7253-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46313706356915,"sku":"ES7253-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/sos-2-rabbit-polyclonal-antibody-es7253","provider":"AFSBio Inc.","version":"1.0","type":"link"}